PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease-Reference-Cited by-同舟云学术

PROTAC-Induced Glycogen Synthase Kinase 3β Degradation as a Potential Therapeutic Strategy for Alzheimer’s Disease

Published:2023-05-23 Issue:11 Volume:14 Page:1963-1970
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Guardigni Melissa¹,Pruccoli Letizia¹,Santini Alan¹,Simone Angela De²,Bersani Matteo²,Spyrakis Francesca²^ORCID,Frabetti Flavia³,Uliassi Elisa⁴^ORCID,Andrisano Vincenza¹^ORCID,Pagliarani Barbara¹,Fernández-Gómez Paula⁵,Palomo Valle⁵⁶,Bolognesi Maria Laura⁴^ORCID,Tarozzi Andrea¹^ORCID,Milelli Andrea¹^ORCID

Affiliation:

1. Department for Life Quality Studies, Alma Mater Studiorum-University of Bologna, Corso d’Augusto 237, 47921 Rimini, Italy

2. Department of Drug Science and Technology, University of Turin, Via Pietro Giuria 9, 10125 Torino, Italy

3. Department of Medical and Surgical Sciences, Alma Mater Studiorum-University of Bologna, Via Belmeloro 8, 40126 Bologna, Italy

4. Department of Pharmacy and Biotechnology, Alma Mater Studiorum-University of Bologna, Via Belmeloro 6, 40126 Bologna, Italy

5. Instituto Madrileño de Estudios Avanzados en Nanociencia (IMDEA-Nanociencia), C/Faraday 9, 28049 Madrid, Spain

6. Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, Av. de Monforte de Lemos, 5, 28029 Madrid, Spain

Funder

Universit?? di Bologna

Ministero dell???Istruzione, dell???Universit?? e della Ricerca

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.3c00096

Reference34 articles.

1. Glycogen synthase kinase-3 (GSK3): Regulation, actions, and diseases

2. GSK3 Function in the Brain during Development, Neuronal Plasticity, and Neurodegeneration