Mechanisms behind the Fibrillation and Toxicity of Insulin Fibrils on Neuron Cells by Engineered Curcumin Analogs

Author:

Akbarian Mohsen123,Bahmani Marzieh14,Chen Shu-Hui3,Yousefi Reza56ORCID,Mohammadi-Samani Soliman12,Tayebi Lobat7ORCID,Panahi Farhad8ORCID,Farjadian Fatemeh1ORCID

Affiliation:

1. Pharmaceutical Sciences Research Center, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz7146864685, Iran

2. Department of Pharmaceutics, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz7146864685, Iran

3. Department of Chemistry, National Cheng Kung University, Tainan701, Taiwan

4. Department of Science, Medicine and Health, School of Chemistry and Molecular Bioscience, University of Wollongong, NSW, Wollongong2522, Australia

5. Institute of Biochemistry and Biophysics (IBB), University of Tehran, Tehran1417466191, Iran

6. Protein Chemistry Laboratory, Department of Biology, College of Sciences, Shiraz University, Shiraz7193371, Iran

7. School of Dentistry, Marquette University, Milwaukee, Wisconsin53233-2186, United States

8. Institut für Organische Chemie, Albert-Ludwigs-Universität Freiburg, Albertstraße 21, 79104 Freiburg im Breisgau, Germany

Funder

Iran National Science Foundation

Shiraz University of Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

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