Synthesis and Biological Evaluation of JAHAs: Ferrocene-Based Histone Deacetylase Inhibitors-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of JAHAs: Ferrocene-Based Histone Deacetylase Inhibitors

Published:2011-03-18 Issue:5 Volume:2 Page:358-362
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Spencer John¹,Amin Jahangir¹,Wang Minghua²,Packham Graham³,Alwi Sharifah S. Syed³,Tizzard Graham J.⁴,Coles Simon J.⁴,Paranal Ronald M.⁵,Bradner James E.⁵,Heightman Tom D.²

Affiliation:

1. School of Science at Medway, University of Greenwich, Chatham, ME4 4TB, United Kingdom

2. Structural Genomics Consortium, University of Oxford, Old Road Campus Research Building, Old Road Campus, Roosevelt Drive, Headington, Oxford OX3 7DQ, United Kingdom

3. Cancer Research UK Centre, University of Southampton, Faculty of Medicine, Mailpoint 824, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, United Kingdom

4. UK National Crystallography Service, School of Chemistry, University of Southampton, Highfield, Southampton, SO17 1BJ, United Kingdom

5. Dana-Farber Cancer Institute, 44 Binney Street, Dana Building, D510D, Boston, Massachusetts 02115, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml100295v

Reference27 articles.

1. Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

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3. Dimethyl sulfoxide to vorinostat: development of this histone deacetylase inhibitor as an anticancer drug