Antimalarial, Antitrypanosomal, and Antileishmanial Activities and Cytotoxicity of Bis(9-amino-6-chloro-2-methoxyacridines): Influence of the Linker-Reference-Cited by-同舟云学术

Antimalarial, Antitrypanosomal, and Antileishmanial Activities and Cytotoxicity of Bis(9-amino-6-chloro-2-methoxyacridines): Influence of the Linker

Published:2000-06-17 Issue:14 Volume:43 Page:2646-2654
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Girault Sophie¹,Grellier Philippe¹,Berecibar Amaya¹,Maes Louis¹,Mouray Elisabeth¹,Lemière Pascal¹,Debreu Marie-Ange¹,Davioud-Charvet Elisabeth¹,Sergheraert Christian¹

Affiliation:

1. UMR 8525 CNRS, Université de Lille II, Institut de Biologie et Institut Pasteur de Lille, 1 rue du Professeur Calmette, BP 447, 59021 Lille, France, Muséum National d'Histoire Naturelle, Biologie et Evolution des Parasites, CNRS - EP1790, 61 rue Buffon, 75005 Paris, France, and Tibotec, L11 Gen. de Wittelaan, B-32800 Mechelen, Belgium

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm990946n

Reference40 articles.

1. Antimalarial drug resistance: the pace quickens

2. Malarial haemozoin/β-haematin supports haem polymerization in the absence of protein

3. Inhibition of glutathione-dependent degradation of heme by chloroquine and amodiaquine as a possible basis for their antimalarial mode of action

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