High-Performance Self-Cascade Pyrite Nanozymes for Apoptosis–Ferroptosis Synergistic Tumor Therapy

Author:

Meng Xiangqin12,Li Dandan3,Chen Lei13,He Helen4,Wang Qian1,Hong Chaoyi1,He Jiuyang1,Gao Xingfa5,Yang Yili6,Jiang Bing7,Nie Guohui8,Yan Xiyun127ORCID,Gao Lizeng17ORCID,Fan Kelong17ORCID

Affiliation:

1. CAS Engineering Laboratory for Nanozyme, Key Laboratory of Protein and Peptide Pharmaceutical, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China

2. School of Future Technology, University of Chinese Academy of Sciences, Beijing 101408, China

3. Department of Pharmacology, School of Medicine, Institute of Translational Medicine, Yangzhou University, Yangzhou 225001, Jiangsu, China

4. School of Life Sciences, Tsinghua University, Beijing 100084, China

5. Laboratory of Theoretical and Computational Nanoscience, National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing 100190, China

6. Suzhou Institute of Systems Medicine, Center for Systems Medicine, Chinese Academy of Medicine Sciences, Suzhou 215123, Jiangsu, China

7. Nanozyme Medical Center, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450052, Henan, China

8. Department of Otolaryngology and Institute of Translational Medicine, Shenzhen Second People’s Hospital/The First Affiliated Hospital of Shenzhen University, Health Science Center, Shenzhen 518035, Guangdong, China

Funder

Ministry of Science and Technology of the People's Republic of China

Natural Science Foundation of Jiangsu Province

Youth Innovation Promotion Association of the Chinese Academy of Sciences

National Natural Science Foundation of China

Chinese Academy of Sciences

CAS Interdisciplinary Innovation Team

Sanming Project of Medicine in Shenzhen

Publisher

American Chemical Society (ACS)

Subject

General Physics and Astronomy,General Engineering,General Materials Science

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