Dual-Sensitive Nanomicelles Enhancing Systemic Delivery of Therapeutically Active Antibodies Specifically into the Brain

Author:

Xie Jinbing12ORCID,Gonzalez-Carter Daniel1ORCID,Tockary Theofilus A.1ORCID,Nakamura Noriko13,Xue Yonger4,Nakakido Makoto3,Akiba Hiroki3,Dirisala Anjaneyulu1,Liu Xueying1,Toh Kazuko1,Yang Tao1,Wang Zengtao4,Fukushima Shigeto1,Li Junjie1,Quader Sabina1ORCID,Tsumoto Kouhei3ORCID,Yokota Takanori5,Anraku Yasutaka13,Kataoka Kazunori16ORCID

Affiliation:

1. Innovation Center of NanoMedicine, Kawasaki Institute of Industrial Promotion, 3-25-14 Tonomachi, Kawasaki-ku, Kawasaki 210-0821, Japan

2. Jiangsu Key Laboratory of Molecular Imaging and Functional Imaging, Department of Radiology, Zhongda Hospital, Medical School of Southeast University, 87 Dingjiaqiao, Nanjing 210009, China

3. Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan

4. Department of Pharmacy, Shanghai Jiaotong University, 800 Dongchun Road, Shanghai 200240, China

5. Department of Neurology and Neurological Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan

6. Institute for Future Initiatives, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

Funder

Ministry of Education, Culture, Sports, Science and Technology

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

Japan Science and Technology Agency

Publisher

American Chemical Society (ACS)

Subject

General Physics and Astronomy,General Engineering,General Materials Science

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