An Isoaurone and Other Constituents fromTrichosanthes kirilowiiSeeds Inhibit Hypoxia-Inducible Factor-1 and Nuclear Factor-κB-Reference-Cited by-同舟云学术

An Isoaurone and Other Constituents fromTrichosanthes kirilowiiSeeds Inhibit Hypoxia-Inducible Factor-1 and Nuclear Factor-κB

Published:2010-05-14 Issue:6 Volume:73 Page:1167-1169
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Dat Nguyen Tien¹,Jin Xuejun¹,Hong Young-Soo¹,Lee Jung Joon¹

Affiliation:

1. Center for Molecular Cancer Research, Korean Research Institute of Biosciences and Biotechnology, 685-1 Ochang, Chungbuk 363-883, Korea, and Laboratory of Organic Chemistry, Institute of Natural Product Chemistry, Vietnam Academy of Science and Technology, Hanoi, Vietnam

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/np900820p

Reference34 articles.

1. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.

2. HIF-1 as a target for drug development

3. Evaluation of HIF-1 inhibitors as anticancer agents

4. Regulation and Function of NF-κB Transcription Factors in the Immune System

5. Series Introduction: The transcription factor NF-κB and human disease

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