Docking Study Yields Four Novel Inhibitors of the Protooncogene Pim-1 Kinase
Author:
Affiliation:
1. Vertex Pharmaceuticals, Incorporated, 130 Waverly Street, Cambridge, Massachusetts, 02139
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm701248t
Reference17 articles.
1. Murine leukemia virus-induced T-cell lymphomagenesis: Integration of proviruses in a distinct chromosomal region
2. Developmental expression of Pim kinases suggests functions also outside of the hematopoietic system
3. Pim-1: A serine/threonine kinase with a role in cell survival, proliferation, differentiation and tumorigenesis
4. The human protooncogene product p33pim is expressed during fetal hematopoiesis and in diverse leukemias.
5. The serine/threonine kinase Pim-1
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