1. Research Center for Environmental Quality Management, Kyoto University, Otsu, Shiga, 520-0811, Japan, Department of Environmental Engineering, National Cheng Kung University, Tainan, 70101, Taiwan, Department of Pathology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, 431-3192, Japan, and Department of Environmental Oncology, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, 807-8555, Japan