Isomerization of an Aspartic Acid Residue in the Complementarity-Determining Regions of a Recombinant Antibody to Human IgE: Identification and Effect on Binding Affinity-Reference-Cited by-同舟云学术

Isomerization of an Aspartic Acid Residue in the Complementarity-Determining Regions of a Recombinant Antibody to Human IgE: Identification and Effect on Binding Affinity

Published:1996-01-01 Issue:6 Volume:35 Page:1897-1903
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Cacia Jerry¹,Keck Rodney¹,Presta Leonard G.¹,Frenz John¹

Affiliation:

1. Departments of Manufacturing Sciences, Analytical Chemistry, and Immunology, Genentech Inc., 460 Pt. San Bruno Boulevard, South San Francisco, California 94080

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi951526c

Reference25 articles.

1. Stoichiometric methylation of porcine adrenocorticotropin by protein carboxyl methyltransferase requires deamidation of asparagine 25. Evidence for methylation at the alpha-carboxyl group of atypical L-isoaspartyl residues.

2. The protein data bank: A computer-based archival file for macromolecular structures

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