Reshaping Tumor Immune Microenvironment through Acidity-Responsive Nanoparticles Featured with CRISPR/Cas9-Mediated Programmed Death-Ligand 1 Attenuation and Chemotherapeutics-Induced Immunogenic Cell Death

Author:

Tu Kun1,Deng Huan12,Kong Li1,Wang Yi1,Yang Ting1,Hu Qian1,Hu Mei1,Yang Conglian1,Zhang Zhiping134ORCID

Affiliation:

1. Tongji School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

2. College of Life Science and Health, Wuhan University of Science and Technology, Wuhan 430065, China

3. National Engineering Research Center for Nanomedicine, Huazhong University of Science and Technology, Wuhan 430030, China

4. Hubei Engineering Research Center for Novel Drug Delivery System, Huazhong University of Science and Technology, Wuhan 430030, China

Funder

Henan University of Science and Technology

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

General Materials Science

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