Structure−Activity Relationships for a Novel Series of Citalopram (1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile) Analogues at Monoamine Transporters-Reference-Cited by-同舟云学术

Structure−Activity Relationships for a Novel Series of Citalopram (1-(3-(Dimethylamino)propyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile) Analogues at Monoamine Transporters

Published:2010-07-30 Issue:16 Volume:53 Page:6112-6121
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhang Peng¹,Cyriac George¹,Kopajtic Theresa²,Zhao Yongfang³,Javitch Jonathan A.³,Katz Jonathan L.²,Newman Amy Hauck¹

Affiliation:

1. Medicinal Chemistry Section, National Institute on Drug Abuse-Intramural Research Program, National Institutes of Health, 333 Cassell Drive, Baltimore, Maryland 21224

2. Psychobiology Section, National Institute on Drug Abuse-Intramural Research Program, National Institutes of Health, 251 Bayview Boulevard, Baltimore, Maryland 21224

3. Center for Molecular Recognition and Departments of Psychiatry and Pharmacology, Columbia University College of Physicians and Surgeons, New York, New York 10032

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm1005034

Reference40 articles.

1. Recent Developments in the Design of Anti-Depressive Therapies: Targeting the Serotonin Transporter

2. Escitalopram

3. Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

4. Coordination of Na+ by Monoamine Ligands in Dopamine, Norepinephrine, and Serotonin Transporters

5. Binding and Orientation of Tricyclic Antidepressants within the Central Substrate Site of the Human Serotonin Transporter

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