Quantification of Binding of Small Molecules to Native Proteins Overexpressed in Living Cells-Reference-Cited by-同舟云学术

Quantification of Binding of Small Molecules to Native Proteins Overexpressed in Living Cells

Published:2023-12-20 Issue:1 Volume:146 Page:187-200
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Yin Yuwen¹,Zhao Serena Li¹,Rane Digamber¹,Lin Zhihong²,Wu Meng¹²^ORCID,Peterson Blake R.¹²^ORCID

Affiliation:

1. Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, The Ohio State University, 500 W. 12th Ave., Columbus, Ohio 43210, United States

2. The Ohio State University Comprehensive Cancer Center─Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, 460 W. 10th Ave., Columbus, Ohio 43210, United States

Funder

National Cancer Institute

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.3c07488

Reference91 articles.

1. Estimation of clinical trial success rates and related parameters

2. Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials

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4. How to measure and evaluate binding affinities

5. Proteome complexity and the forces that drive proteome imbalance

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