Modified Acidic Nonsteroidal Anti-Inflammatory Drugs as Dual Inhibitors of mPGES-1 and 5-LOX-Reference-Cited by-同舟云学术

Modified Acidic Nonsteroidal Anti-Inflammatory Drugs as Dual Inhibitors of mPGES-1 and 5-LOX

Published:2012-10-09 Issue:20 Volume:55 Page:8958-8962
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Elkady Mahmoud¹,Nieß Raimund¹,Schaible Anja M.²,Bauer Julia¹,Luderer Susann¹,Ambrosi Giulia¹,Werz Oliver²,Laufer Stefan A.¹

Affiliation:

1. Department of Pharmaceutical/Medicinal Chemistry, Eberhard Karls University, Tübingen, Auf der Morgenstelle 8, D-72076 Tübingen, Germany

2. Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University, Jena, Philosophenweg 14, D-07743 Jena, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm3010543

Reference18 articles.

1. Clinical significance of prostaglandin E synthase expression in gastric cancer tissue

2. Expression Analysis of the Prostaglandin E2 Production Pathway in Human Pancreatic Cancers

3. Cardiovascular Risk and Inhibition of Cyclooxygenase

4. Pharmacophore Modeling and Virtual Screening for Novel Acidic Inhibitors of Microsomal Prostaglandin E2 Synthase-1 (mPGES-1)

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