Phosphatidylinositol 3-Kinase (PI3K) and Phosphatidylinositol 3-Kinase-Related Kinase (PIKK) Inhibitors: Importance of the Morpholine Ring-Reference-Cited by-同舟云学术

Phosphatidylinositol 3-Kinase (PI3K) and Phosphatidylinositol 3-Kinase-Related Kinase (PIKK) Inhibitors: Importance of the Morpholine Ring

Published:2014-12-05 Issue:1 Volume:58 Page:41-71
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Andrs Martin¹²,Korabecny Jan¹,Jun Daniel¹²,Hodny Zdenek³,Bartek Jiri³⁴,Kuca Kamil¹

Affiliation:

1. Biomedical Research Center, University Hospital Hradec Kralove, Sokolska 81, 500 05 Hradec Kralove, Czech Republic

2. Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Trebesska 1575, 500 01 Hradec Kralove, Czech Republic

3. Department of Genome Integrity, Institute of Molecular Genetics of the ASCR, v.v.i., Videnska 1083, 142 20 Prague, Czech Republic

4. Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100 Copenhagen, Denmark

Funder

Ministerstvo Zdravotnictv? Cesk? Republiky

Akademie ved Cesk? Republiky

St?tn? rozpocet Cesk? Republiky

University Hospital Hradec Kr?lov?

Faculty of Military Health Sciences, University of Defence

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm501026z

Reference255 articles.

1. Phospholipid signaling

2. Synthesis and Function of 3-Phosphorylated Inositol Lipids

3. Phosphoinositide 3-kinases: A conserved family of signal transducers

4. Phosphoinositide Kinases as Enzymes that Produce Versatile Signaling Lipids, Phosphoinositides

5. Signaling by Distinct Classes of Phosphoinositide 3-Kinases

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