Structural Insight into Tetrameric hTRPV1 from Homology Modeling, Molecular Docking, Molecular Dynamics Simulation, Virtual Screening, and Bioassay Validations
Author:
Affiliation:
1. Laboratory of Cancer Biology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, United States
Funder
National Cancer Institute
National Institute on Drug Abuse
Publisher
American Chemical Society (ACS)
Subject
Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ci5007189
Reference55 articles.
1. Stereospecific High-affinity TRPV1 Antagonists: Chiral N-(2-Benzyl-3-pivaloyloxypropyl) 2-[4-(methylsulfonylamino)phenyl]propionamide Analogues
2. Functionally Important Amino Acid Residues in the Transient Receptor Potential Vanilloid 1 (TRPV1) Ion Channel - An Overview of the Current Mutational Data
3. TRP Channels
4. Unravelling the Mystery of Capsaicin: A Tool to Understand and Treat Pain
5. TRPV1 structures in distinct conformations reveal activation mechanisms
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