Pharmacokinetic/Pharmacodynamic Modeling To Predict the Antiplatelet Effect of the Ticagrelor-Loaded Self-Microemulsifying Drug Delivery System in Rats-Reference-Cited by-同舟云学术

Pharmacokinetic/Pharmacodynamic Modeling To Predict the Antiplatelet Effect of the Ticagrelor-Loaded Self-Microemulsifying Drug Delivery System in Rats

Published:2020-02-13 Issue:4 Volume:17 Page:1079-1089
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Na Young-Guk¹^ORCID,Byeon Jin-Ju¹,Kim Min-Ki¹,Han Min-Gu¹,Cho Cheong-Weon¹,Baek Jong-Suep²,Lee Hong-Ki¹,Shin Young G.¹

Affiliation:

1. College of Pharmacy, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 34134, Republic of Korea

2. Department of Herbal Medicine Resource, Kangwon National University, 346 Hwangjo-gil, Dogye-eup, Samcheok-si, Gangwon-do 25949, Republic of Korea

Funder

National Research Foundation of Korea

Kangwon National University

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.9b00964

Reference39 articles.

1. Thrombosis

2. Platelets in inflammation and atherogenesis

3. Ticagrelor: The First Reversibly Binding Oral P2Y12Receptor Antagonist

4. Pharmacokinetics, pharmacodynamics, safety and tolerability of multiple ascending doses of ticagrelor in healthy volunteers

5. Comparison of ticagrelor with clopidogrel in patients with a planned invasive strategy for acute coronary syndromes (PLATO): a randomised double-blind study

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