Development of an Amorphous Solid Dispersion Formulation for Mitigating Mechanical Instability of Crystalline Form and Improving Bioavailability for Early Phase Clinical Studies-Reference-Cited by-同舟云学术

Development of an Amorphous Solid Dispersion Formulation for Mitigating Mechanical Instability of Crystalline Form and Improving Bioavailability for Early Phase Clinical Studies

Published:2023-04-03 Issue:5 Volume:20 Page:2452-2464
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Chiang Cheng W.^ORCID,Lubach Joseph W.^ORCID,Chen Tao^ORCID,Chin Steven^ORCID,Ly Justin,Zhang Wei^ORCID,Hou Hao Helen,Nagapudi Karthik

Funder

Genentech Small Molecule Pharmaceutical Sciences department

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.2c01056

Reference55 articles.

1. Quantitative Impurity Rejection Analysis for Crystallization

2. Quantifying Dry Milling in Pharmaceutical Processing: A Review on Experimental and Modeling Approaches

3. Understanding the Effect of API Properties on Bioavailability Through Absorption Modeling

4. Phase transformation considerations during process development and manufacture of solid oral dosage forms

5. Evaluation of drug physical form during granulation, tabletting and storage

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