Interlaboratory Variability in the Madin–Darby Canine Kidney Cell Proteome-Reference-Cited by-同舟云学术

Interlaboratory Variability in the Madin–Darby Canine Kidney Cell Proteome

Published:2023-06-07 Issue:7 Volume:20 Page:3505-3518
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Harwood Matthew D.¹^ORCID,Zettl Katharina²,Weinheimer Manuel³,Pilla-Reddy Venkatesh⁴,Shen Hong⁵^ORCID,Jacobs Frank⁶,Chu Xiaoyan⁷,Huth Felix⁸,Nakakariya Masanori⁹,Chothe Paresh P.¹⁰,Neuhoff Sibylle¹^ORCID,Wiśniewski Jacek R.²^ORCID

Affiliation:

1. Certara UK Ltd (Simcyp Division), Sheffield S1 2BJ, U.K.

2. Biochemical Proteomics Group, Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried 82152, Germany

3. Quantitative, Translational & ADME Sciences, AbbVie Deutschland GmbH & Co. KG, Ludwigshafen 67061, Germany

4. Clinical Pharmacology and Quantitative Pharmacology, Vaccines and Immunotherapies, Neuroscience and Clinical Immunogenicity, AstraZeneca, Cambridge CB2 0AA, U.K.

5. Drug Metabolism and Pharmacokinetics, Bristol Myers Squibb, Princeton, New Jersey 08543, United States

6. Preclinical Sciences Translational Safety, Janssen Pharmaceutical Companies of Johnson & Johnson, Beerse 2340, Belgium

7. ADME and Discovery Toxicity, Merck & Co., Inc., Rahway, New Jersey 07065, United States

8. Novartis Institutes for BioMedical Research, Basel 4056, Switzerland

9. Global Drug Metabolism and Pharmacokinetics, Takeda Development Center Americas, Inc. (TDCA), 9625 Towne Centre Drive, San Diego, California 92121, United States

10. Drug Metabolism and Pharmacokinetics, Vertex Pharmaceuticals, Boston, Massachusetts 02210, United States

Funder

Max-Planck-Gesellschaft

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.3c00108

Reference81 articles.

1. Development of a new permeability assay using low‐efflux MDCKII cells

2. Characterization of an Established Line of Canine Kidney Cells (MDCK).

3. Established Kidney Cell Lines of Normal Adult Bovine and Ovine Origin.

4. Endogenous drug transporters in in vitro and in vivo models for the prediction of drug disposition in man

5. Establishment of Optimized MDCK Cell Lines for Reliable Efflux Transport Studies

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