1. Laboratory of Biochemistry and Molecular Biology, Graduate School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan
2. Department of Pharmacokinetics and Nonclinical Safety, Nippon Boehringer Ingelheim Co., Kobe, Hyogo 650-0047, Japan
3. Laboratory of Functional Organoid for Drug Discovery, National Institutes of Biomedical Innovation, Health and Nutrition, Osaka 567-0085, Japan
4. Laboratory of Biochemistry and Molecular Biology, School of Pharmaceutical Sciences, Osaka University, Osaka 565-0871, Japan
5. Department of Gastroenterology and Hepatology, School of Medicine, Sapporo Medical University, Hokkaido 060-8556, Japan
6. Department of Medical Oncology, Keiyukai Sapporo Hospital, Hokkaido 003-0027, Japan
7. Integrated Frontier Research for Medical Science Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Osaka 565-0871, Japan
8. Global Center for Medical Engineering and Informatics, Osaka University, Osaka 565-0871, Japan