Clofazimine p<i>K</i><sub>a</sub> Determination by Potentiometry and Spectrophotometry: Reverse Cosolvent Dependence as an Indicator of the Presence of Dimers in Aqueous Solutions-Reference-Cited by-同舟云学术

Clofazimine pK_a Determination by Potentiometry and Spectrophotometry: Reverse Cosolvent Dependence as an Indicator of the Presence of Dimers in Aqueous Solutions

Published:2023-04-25 Issue:6 Volume:20 Page:3160-3169
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Verbić Tatjana Ž.¹²^ORCID,Tam Kin Y.³,Veljković Dušan Ž.¹^ORCID,Serajuddin Abu T. M.²^ORCID,Avdeef Alex⁴

Affiliation:

1. University of Belgrade - Faculty of Chemistry, Studentski trg 12-16, 11000 Belgrade, Republic of Serbia

2. College of Pharmacy and Health Sciences, St. John’s University, 8000 Utopia Parkway, Queens, New York 11439, United States

3. Department of Pharmaceutical Sciences, Faculty of Health Sciences, University of Macau, Macau 00000, China

4. in-ADME Research, 1732 First Avenue #102, New York, New York 10128, United States

Funder

St. John's University

Bureau of Educational and Cultural Affairs

Institute of International Education

Ministarstvo nauke, tehnolo?kog razvoja i inovacija

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.molpharmaceut.3c00172

Reference42 articles.

1. Predicting Solubility of Newly-Approved Drugs (2016–2020) with a Simple ABSOLV and GSE(Flexible-Acceptor) Consensus Model Outperforming Random Forest Regression

2. Trends in PhysChem Properties of Newly Approved Drugs over the Last Six Years; Predicting Solubility of Drugs Approved in 2021

3. Nortriptyline Hydrochloride Solubility-pH Profiles in a Saline Phosphate Buffer: Drug-Phosphate Complexes and Multiple pH_max Domains with a Gibbs Phase Rule “Soft” Constraints

4. Solubility-pH profile of desipramine hydrochloride in saline phosphate buffer: Enhanced solubility due to drug-buffer aggregates

5. Anomalous Solubility Behavior of Several Acidic Drugs

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