Generation of Monoclonal Antibody Fragments Binding the Native γ-Secretase Complex for Use in Structural Studies
Author:
Affiliation:
1. Brain Mind Institute, School of Life Sciences, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland
2. Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM U964, CNRS UMR7104, Illkirch, France
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi300997e
Reference44 articles.
1. Structural and Functional Determinants of γ-Secretase, an Intramembrane Protease Implicated in Alzheimers Disease
2. Intramembrane Proteases--Mixing Oil and Water
3. Presenilin diversifies its portfolio
4. Processing of the Synaptic Cell Adhesion Molecule Neurexin-3β by Alzheimer Disease α- and γ-Secretases
5. What the halted phase III γ-secretase inhibitor trial may (or may not) be telling us
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1. The lipidome associated with the γ-secretase complex is required for its integrity and activity;Biochemical Journal;2016-01-25
2. Learning by Failing: Ideas and Concepts to Tackle γ-Secretases in Alzheimer's Disease and Beyond;Annual Review of Pharmacology and Toxicology;2015-01-06
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