Synthesis of Flufenamic Acid: An Organic Chemistry Lab Sequence Using Boronic Acids and Nitrosoarenes under Transition-Metal-Free Conditions
Author:
Affiliation:
1. Instituto Pluridisciplinar, Universidad Complutense, Campus de Excelencia Internacional Moncloa, Paseo de Juan XXIII, 1, 28040 Madrid, Spain
Funder
Ministerio de Ciencia e Innovaci?n
Publisher
American Chemical Society (ACS)
Subject
Education,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.jchemed.8b00824
Reference69 articles.
1. aParke Davies & Co. N-(3-Trifluoromethylphenyl)anthranilic acid antiinflammatory drug. U.S. Patent FRM134119620702, 1962.
2. b Pharmaceutical Manufacturing Encyclopedia, 3rd ed. William Andrew Publishing: Norwich, NY, 2007; p 1644.
3. Flufenamic Acid
4. An Efficient Microscale Procedure for the Synthesis of Aspirin
5. Synthesis of Aspirin: A General Chemistry Experiment
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