Total Synthesis in Search of Potent Antibody–Drug Conjugate Payloads. From the Fundamentals to the Translational
Author:
Affiliation:
1. Department of Chemistry, BioScience Research Collaborative, Rice University, 6100 Main Street, Houston, Texas 77005, United States
Funder
Welch Foundation
Bristol-Myers Squibb
Cancer Prevention and Research Institute of Texas
U.S. Department of Health and Human Services
AbbVie Stemcentrx, LLC.
Publisher
American Chemical Society (ACS)
Subject
General Medicine,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.accounts.8b00537
Reference84 articles.
1. Ehrlich, P. Beiträge zur experimentellen Pathologie und Chemotherapie; Akademische Verlagsgesellschaft: Leipzig, 1909; pp 165–202.
2. Strategies and challenges for the next generation of antibody–drug conjugates
3. Novel antibody–antibiotic conjugate eliminates intracellular S. aureus
4. Continuous cultures of fused cells secreting antibody of predefined specificity
5. The Role of Natural Product Chemistry in Drug Discovery
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