Identification of a Novel Cardenolide (2‘ ‘-Oxovoruscharin) from Calotropis procera and the Hemisynthesis of Novel Derivatives Displaying Potent in Vitro Antitumor Activities and High in Vivo Tolerance:  Structure−Activity Relationship Analyses

Author:

Van Quaquebeke Eric1,Simon Gentiane1,André Aurélie1,Dewelle Janique1,Yazidi Mohamed El1,Bruyneel Frederic1,Tuti Jerome1,Nacoulma Odile1,Guissou Pierre1,Decaestecker Christine1,Braekman Jean-Claude1,Kiss Robert1,Darro Francis1

Affiliation:

1. Unibioscreen SA, 40 avenue Joseph Wybran, 1070 Bruxelles, Belgique, Laboratoire de Biochimie et de Chimie Appliquée, Département de Biochimie/Microbiologie, 03 BP 7021, Université de Ouagadougou, Ouagadougou 03, Burkina Faso, Laboratoire de Pharmacologie, Faculté des Sciences de la Santé, 01 BP 1806, Université de Ouagadougou, Ouagadougou, Burkina Faso, Laboratoire de Toxicologie, Institut de Pharmacie, Université Libre de Bruxelles, Bruxelles, and Laboratoire de Chimie Organique, Faculté des Sciences,...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Cited by 146 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Mycotoxin detection in selected medicinal plants using chromatographic techniques;Biomedical Chromatography;2024-01-30

2. A comprehensive review of the ethnomedicinal uses, phytochemistry, and pharmacology of potential anticancer plants of the flora of Africa;Advances in Botanical Research;2024

3. Exploring the Potential of Calotropis procera in Pharmacological Approaches;Medicinal Plants - Chemical, Biochemical, and Pharmacological Approaches [Working Title];2023-11-14

4. The Indian Cytotoxic Weed Flora and Their Phytochemicals;Alternative Remedies and Natural Products for Cancer Therapy: An Integrative Approach;2023-10-31

5. Promiscuous CYP87A enzyme activity initiates cardenolide biosynthesis in plants;Nature Plants;2023-09-18

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3