Global Structure of the Intrinsically Disordered Protein Tau Emerges from Its Local Structure-Reference-Cited by-同舟云学术

Global Structure of the Intrinsically Disordered Protein Tau Emerges from Its Local Structure

Published:2022-03-01 Issue:3 Volume:2 Page:673-686
ISSN:2691-3704
Container-title:JACS Au
language:en
Short-container-title:JACS Au

Author:

Stelzl Lukas S.¹²³⁴^ORCID,Pietrek Lisa M.¹^ORCID,Holla Andrea⁵,Oroz Javier⁶⁷,Sikora Mateusz¹⁸^ORCID,Köfinger Jürgen¹^ORCID,Schuler Benjamin⁵⁹^ORCID,Zweckstetter Markus⁶¹⁰^ORCID,Hummer Gerhard¹¹¹^ORCID

Affiliation:

1. Department of Theoretical Biophysics, Max Planck Institute of Biophysics, Max-von-Laue-Straße 3, 60438 Frankfurt am Main, Germany

2. Faculty of Biology, Johannes Gutenberg University Mainz, Gresemundweg 2, 55128 Mainz, Germany

3. KOMET 1, Institute of Physics, Johannes Gutenberg University Mainz, 55099 Mainz, Germany

4. Institute of Molecular Biology (IMB), 55128 Mainz, Germany

5. Department of Biochemistry, University of Zurich, 8057 Zurich, Switzerland

6. German Center for Neurodegenerative Diseases (DZNE), von-Siebold-Str. 3a, 37075 Göttingen, Germany

7. Rocasolano Institute for Physical Chemistry, CSIC, Serrano 119, 28006 Madrid, Spain

8. Faculty of Physics, University of Vienna, Kolingasse 14-16, 1090 Vienna, Austria

9. Department of Physics, University of Zurich, 8057 Zurich, Switzerland

10. Department for NMR-based Structural Biology, Max Planck Institute for Multidisciplinary Sciences, Am Faßberg 11, 37077 Göttingen, Germany

11. Institute for Biophysics, Goethe University Frankfurt, Max-von-Laue-Straße 9, 60438 Frankfurt am Main, Germany

Funder

Schweizerischer Nationalfonds zur F??rderung der Wissenschaftlichen Forschung

Austrian Science Fund

Deutsche Forschungsgemeinschaft

Johannes Gutenberg-Universit??t Mainz

Max-Planck-Gesellschaft

European Commission

Ministry of Science, Continuing Education and Culture of Rhineland-Palatinate

Ministerium f??r Wissenschaft, Weiterbildung und Kultur

Publisher

American Chemical Society (ACS)

Subject

General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jacsau.1c00536

Reference106 articles.

1. Tau stabilizes microtubules by binding at the interface between tubulin heterodimers

2. Tau in physiology and pathology

3. Local Nucleation of Microtubule Bundles through Tubulin Concentration into a Condensed Tau Phase

4. Liquid–liquid phase separation of the microtubule-binding repeats of the Alzheimer-related protein Tau

5. RNA stores tau reversibly in complex coacervates

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