Biosynthetic Crossover of 5-Lipoxygenase and Cyclooxygenase-2 Yields 5-Hydroxy-PGE2 and 5-Hydroxy-PGD2-Reference-Cited by-同舟云学术

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Biosynthetic Crossover of 5-Lipoxygenase and Cyclooxygenase-2 Yields 5-Hydroxy-PGE2 and 5-Hydroxy-PGD2

Published:2021-08-04 Issue:9 Volume:1 Page:1380-1388
ISSN:2691-3704
Container-title:JACS Au
language:en
Short-container-title:JACS Au

Author:

Nakashima Fumie¹,Suzuki Takashi¹,Gordon Odaine N.¹,Golding Dominic¹,Okuno Toshiaki²^ORCID,Giménez-Bastida Juan A.¹^ORCID,Yokomizo Takehiko²,Schneider Claus¹^ORCID

Affiliation:

1. Division of Clinical Pharmacology, Department of Pharmacology, and Vanderbilt Institute of Chemical Biology, Vanderbilt University Medical School, Nashville, Tennessee 37232, United States

2. Department of Biochemistry, Juntendo University Graduate School of Medicine, Tokyo 113-8421, Japan

Funder

American Heart Association

National Institutes of Health

MEXT/JSPS KAKENHI

Publisher

American Chemical Society (ACS)

Subject

General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jacsau.1c00177

Reference40 articles.

1. Structural and Functional Basis of Cyclooxygenase Inhibition

2. Cyclooxygenases: Structural, Cellular, and Molecular Biology

3. Non-redundant Functions of Cyclooxygenases: Oxygenation of Endocannabinoids

4. Convergent Oxygenation of Arachidonic Acid by 5-Lipoxygenase and Cyclooxygenase-2

5. Biosynthesis of hemiketal eicosanoids by cross-over of the 5-lipoxygenase and cyclooxygenase-2 pathways

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