Synthesis and Anti-HIV Activity of Novel N-1 Side Chain-Modified Analogs of 1-[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT)-Reference-Cited by-同舟云学术

Synthesis and Anti-HIV Activity of Novel N-1 Side Chain-Modified Analogs of 1-[(2-Hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT)

Published:1997-06-01 Issue:12 Volume:40 Page:1845-1854
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pontikis Renée¹,Benhida Rachid¹,Aubertin Anne-Marie¹,Grierson David S.¹,Monneret Claude¹

Affiliation:

1. Institut Curie, Section Recherche, UMR CNRS 176, 26 rue d'Ulm, 75231 Paris Cedex 05, France, Institut de Chimie des Substances Naturelles, UPR CNRS 2301, Avenue de la Terrasse, 91198 Gif-sur-Yvette, France, and Institut de Virologie, Faculté de Médecine, U 74 INSERM, 3 rue Koeberlé, 67000 Strasbourg, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm960765a

Reference47 articles.

1. Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

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3. The Efficacy of Azidothymidine (AZT) in the Treatment of Patients with AIDS and AIDS-Related Complex

4. Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides.

5. In Vivo Activity Against HIV and Favorable Toxicity Profile of 2′,3′-Dideoxyinosine

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