Metabolic Forest: Predicting the Diverse Structures of Drug Metabolites-Reference-Cited by-同舟云学术

Metabolic Forest: Predicting the Diverse Structures of Drug Metabolites

Published:2020-09-03 Issue:10 Volume:60 Page:4702-4716
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Hughes Tyler B.¹^ORCID,Dang Na Le¹^ORCID,Kumar Ayush¹,Flynn Noah R.¹^ORCID,Swamidass S. Joshua¹^ORCID

Affiliation:

1. Department of Pathology and Immunology, Washington University School of Medicine, Campus Box 8118, 660 South Euclid Avenue, St. Louis, Missouri 63110, United States

Funder

U.S. National Library of Medicine

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.0c00360

Reference131 articles.

1. Reducing attrition in drug development: smart loading preclinical safety assessment

2. Can the pharmaceutical industry reduce attrition rates?

3. Phase II and Phase III attrition rates 2011–2012

4. Structural Alert/Reactive Metabolite Concept as Applied in Medicinal Chemistry to Mitigate the Risk of Idiosyncratic Drug Toxicity: A Perspective Based on the Critical Examination of Trends in the Top 200 Drugs Marketed in the United States

5. Idiosyncratic Adverse Drug Reactions: Current Concepts

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