Stability Prediction for Mutations in the Cytosolic Domains of Cystic Fibrosis Transmembrane Conductance Regulator-Reference-Cited by-同舟云学术

Stability Prediction for Mutations in the Cytosolic Domains of Cystic Fibrosis Transmembrane Conductance Regulator

Published:2021-03-15 Issue:4 Volume:61 Page:1762-1777
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Bahia Malkeet Singh¹,Khazanov Netaly¹,Zhou Qingxian²,Yang Zhengrong³^ORCID,Wang Chi⁴,Hong Jeong S.⁵,Rab Andras⁵,Sorscher Eric J.⁵,Brouillette Christie G.⁶,Hunt John F.⁴,Senderowitz Hanoch¹^ORCID

Affiliation:

1. Department of Chemistry, Bar-Ilan University, Ramat-Gan, 5290002, Israel

2. School of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294, United States

3. School of Medicine, Division of Hematology & Oncology, University of Alabama at Birmingham, Birmingham, Alabama 35294, United States

4. 702 Fairchild Center, MC3423, Department of Biological Sciences, Columbia University, New York, New York 10027, United States

5. Department of Paediatrics, Emory University School of Medicine, Atlanta, Georgia 30303, United States

6. Department of Biochemistry & Molecular Genetics, University of Alabama at Birmingham, Birmingham, Alabama 35294, United States

Funder

United States-Israel Binational Science Foundation

Cystic Fibrosis Foundation

Council for Higher Education

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.0c01207

Reference83 articles.

1. Cystic fibrosis: a disease of vulnerability to airway surface dehydration

2. Misfolding of the Cystic Fibrosis Transmembrane Conductance Regulator and Disease

3. C-terminal Truncations Destabilize the Cystic Fibrosis Transmembrane Conductance Regulator without Impairing Its Biogenesis

4. From CFTR biology toward combinatorial pharmacotherapy: expanded classification of cystic fibrosis mutations

5. Physiology of Epithelial Chloride and Fluid Secretion

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