Communication between the Ligand-Binding Pocket and the Activation Function-2 Domain of Androgen Receptor Revealed by Molecular Dynamics Simulations-Reference-Cited by-全球学者库

Communication between the Ligand-Binding Pocket and the Activation Function-2 Domain of Androgen Receptor Revealed by Molecular Dynamics Simulations

Published:2019-01-18 Issue:2 Volume:59 Page:842-857
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Jin Ye¹²,Duan Mojie³^ORCID,Wang Xuwen²,Kong Xiaotian²,Zhou Wenfang²,Sun Huiyong²^ORCID,Liu Hui²,Li Dan²,Yu Huidong⁴,Li Youyong¹^ORCID,Hou Tingjun¹²⁵^ORCID

Affiliation:

1. Institute of Functional Nano and Soft Materials (FUNSOM), Soochow University, Suzhou, Jiangsu 215123, China

2. College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, China

3. Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Center for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan 430071, China

4. Rongene Pharma Co., Ltd., Shenzhen, Guangdong 518054, China

5. State Key Lab of CAD&CG, Zhejiang University, Hangzhou, Zhejiang 310058, China

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

Shenzhen Science and Technology Innovation Commission

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.8b00796