Post-Translational Regulation of CYP450s Metabolism As Revealed by All-Atoms Simulations of the Aromatase Enzyme-Reference-Cited by-同舟云学术

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Post-Translational Regulation of CYP450s Metabolism As Revealed by All-Atoms Simulations of the Aromatase Enzyme

Published:2019-04-29 Issue:6 Volume:59 Page:2930-2940
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Ritacco Ida¹,Spinello Angelo¹^ORCID,Ippoliti Emiliano²^ORCID,Magistrato Alessandra¹^ORCID

Affiliation:

1. CNR-IOM-Democritos c/o International School for Advanced Studies (SISSA), via Bonomea 265, 34136 Trieste, Italy

2. IAS-5/INM-9 Computational Biomedicine Institute and JARA-HPC, Forschungszentrum Jülich, Wilhelm-Johnen-Straße, 52425 Jülich, Germany

Funder

Associazione Italiana per la Ricerca sul Cancro

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jcim.9b00157

Reference99 articles.

1. Protein Phosphorylation and Intermolecular Electron Transfer: A Joint Experimental and Computational Study of a Hormone Biosynthesis Pathway

2. Cytochrome-P450 phosphorylation as a functional switch

3. Phosphorylation of Human Cytochrome P450c17 by p38α Selectively Increases 17,20 Lyase Activity and Androgen Biosynthesis

4. Phosphorylation of Bovine Adrenodoxin by Protein Kinase CK2 Affects the Interaction with Its Redox Partner Cytochrome P450scc (CYP11A1)

5. Aromatase—A Brief Overview

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2. Charged Amino Acids in the Transmembrane Helix Strongly Affect the Enzyme Activity of Aromatase;International Journal of Molecular Sciences;2024-01-24

3. Influence of cholesterol on kinetic parameters for human aromatase (P450 19A1) in phospholipid nanodiscs;Journal of Inorganic Biochemistry;2023-10

4. Switching from Aromatase Inhibitors to Dual Targeting Flavonoid-Based Compounds for Breast Cancer Treatment;Molecules;2023-03-29

5. Recent Advances in Novel Recombinant RNAs for Studying Post-transcriptional Gene Regulation in Drug Metabolism and Disposition;Current Drug Metabolism;2023-03

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