Role of isomerization of initial complexes in the binding of inhibitors to dihydrofolate reductase
Author:
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi00339a010
Reference12 articles.
1. Inhibition of dihydrofolate reductase: effect of NADPH on the selectivity and affinity of diaminobenzylpyrimidines
2. Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 A resolution. I. General features and binding of methotrexate.
3. Carbon-13 nuclear magnetic resonance study of protonation of methotrexate and aminopterin bound to dihydrofolate reductase
4. Protonated state of methotrexate, trimethoprim, and pyrimethamine bound to dihydrofolate reductase
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