Synthesis of 8-Hydroxyquinoline Derivatives as Novel Antitumor Agents

Author:

Chan Sau Hing1,Chui Chung Hin2,Chan Shun Wan1,Kok Stanton Hon Lun1,Chan Dessy1,Tsoi Miriam Yuen Tung1,Leung Polly Hang Mei3,Lam Alfred King Yin4,Chan Albert Sun Chi5,Lam Kim Hung1,Tang Johnny Cheuk On1

Affiliation:

1. State Key Laboratory of Chirosciences, State Key Laboratory of Chinese Medicine and Molecular Pharmacology (Shenzhen), Lo Ka Chung Centre for Natural Anti-Cancer Drug Development, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong SAR, People's Republic of China

2. Clinical Division, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong SAR, People's Republic of China

3. Department of Health Technology & Informatics, The Hong Kong Polytechnic University, Hong Kong SAR, People's Republic of China

4. Department of Pathology, Griffith Medical School and Griffith Health Institute, Griffith University, Gold Coast, Queensland, Australia

5. The President Office, Hong Kong Baptist University, Hong Kong SAR, People's Republic of China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference30 articles.

1. Cancer Statistics, 2008

2. Manfred, H.Alkaloids: Nature's Curse or Blessing?Wiley-VCH:Weinheim, Chichester, 2002; pp1–10,283–312.

3. Karch, S. B.; Cupp, M. J.Toxicology and Clinical Pharmacology of Herbal Products;Humana Press:Totowa, 2000; p11.

4. Enantiomeric separation and quantification of ephedrine-type alkaloids in herbal materials by comprehensive two-dimensional gas chromatography

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