Improved Synthetic Process of Baloxavir Marboxil Intermediate 3-Benzyloxy-4-oxo-4H-pyran-2-carboxylic Acid

Author:

Huang Kongcheng12ORCID,Lu Jianwu32ORCID,Wang Xiaoxu2,Shi Yinfei2,Yang Kaimike4,Yuan Shun2,Wang Yinquan2,Sun Han2,Liu Yuebin2,Sun Xun3ORCID,Wu Taizhi2ORCID

Affiliation:

1. School of Chemistry and Chemical Engineering, Shanghai University of Engineering Science, 333 Longteng Road, Shanghai 201620, China

2. State Key Lab of New Drug & Pharmaceutical Process, Shanghai Institute of Pharmaceutical Industry, China State Institute of Pharmaceutical Industry, 285 Gebaini Road, Shanghai 201203, China

3. Department of Natural Medicine, School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 201203, China

4. Wuhan Britain-China Senior High School, 10 Gutian Ce Road, Wuhan 430061, China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Reference35 articles.

1. Baloxavir Marboxil: The First Cap-Dependent Endonuclease Inhibitor for the Treatment of Influenza

2. Dolutegravir for the treatment of HIV

3. Baloxavir marboxil: the new influenza drug on the market

4. World Health Organization. Influenza (Seasonal). Https://www.who.int/news-room/fact-sheets/detail/influenza-(seasonal) (accessed April 14, 2023).

5. Johns, B. A.; Weatherhead, J. G. Chemical Compounds. WO 2010011815 A1, 2010.

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