Stereoselective Synthesis of ABBV-992 Enabled by a Flow Diazotization and a Partial Reduction of a Pyridone-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

Stereoselective Synthesis of ABBV-992 Enabled by a Flow Diazotization and a Partial Reduction of a Pyridone

Published:2024-07-12 Issue:8 Volume:28 Page:3152-3160
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Brady Patrick B.¹^ORCID,Harper Kaid C.²^ORCID,Sorensen Bryan K.¹,Greszler Stephen N.¹^ORCID,Lai Chunqiu¹,Florjancic Alan S.¹,Zhao Gang¹,Shelat Bhadra H.³,Storer Gregory E.²^ORCID,Henry Rodger F.³,Hansen T. Matthew¹

Affiliation:

1. Centralized Organic Synthesis Group, Small Molecule Therapeutic & Platform Technologies, AbbVie Inc., North Chicago, Illinois 60044, United States

2. Process Research & Development, AbbVie Inc., North Chicago, Illinois 60064, United States

3. Technology and Therapeutic Platforms, AbbVie Inc., North Chicago, Illinois 60044, United States

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.4c00077

Reference59 articles.

1. Role of Bruton’s tyrosine kinase in B cells and malignancies

2. Targeting B cell receptor signalling in cancer: preclinical and clinical advances

3. BTK inhibitors in the treatment of hematological malignancies and inflammatory diseases: mechanisms and clinical studies

4. Ibrutinib and its use in the treatment of chronic lymphocytic leukemia

5. The development of Bruton's tyrosine kinase (BTK) inhibitors from 2012 to 2017: A mini-review

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP