Development of an Optimized Process for the Liver-Targeted Triantennary <i>N</i>-Acetylgalactosamine Ligand-Reference-Cited by-同舟云学术

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Development of an Optimized Process for the Liver-Targeted Triantennary N-Acetylgalactosamine Ligand

Published:2023-12-14 Issue:1 Volume:28 Page:188-209
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Kim Joseph T.¹^ORCID,McPherson Andrew K.¹^ORCID,Rodriguez Andrew A.¹^ORCID,Chen Lijian¹,Lu Yee Fung²,Moskalev Nick²,Upadhyay Sunil K.²,Green Caroline²,Whetsell Miranda²,Xiang-Rong Jiang²,Trofimov Alexander³,Ring Francis¹,Davalos Ashley¹,Gabriel Christopher M.¹,Olsen Phil¹^ORCID

Affiliation:

1. Department of Process Organic Chemistry, Ionis Pharmaceuticals, 2855 Gazelle Court, Carlsbad, California 92010, United States

2. Thermo Fisher Scientific, 6173 E Old Marion Hwy, Florence, South Carolina 29506, United States

3. Boehringer Ingelheim Pharmaceuticals, 900 Ridgebury Rd, Ridgefield, Connecticut 06877, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.3c00281

Reference14 articles.

1. Targeted delivery of oligonucleotides using multivalent protein–carbohydrate interactions

2. Liver-Targeted Delivery of Oligonucleotides with N-Acetylgalactosamine Conjugation

3. The Isolation and Properties of a Rabbit Liver Binding Protein Specific for Asialoglycoproteins

4. The asialoglycoprotein receptor: a model for endocytic transport receptors

5. The asialoglycoprotein receptor: relationships between structure, function, and expression

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