Cerium(III) Chloride-Mediated Stereoselective Reduction of a 4-Substituted Cyclohexanone Using NaBH4

Author:

Maity Prantik1,Gujjar Manjunath1,Vellingiri Raghukumar1,Lakshminarasimhan Thirumalai1,DelMonte Albert J.2ORCID,Young Ian S.2ORCID,Eastgate Martin D.2ORCID,Vaidyanathan Rajappa1ORCID

Affiliation:

1. Chemical Development and API Supply, Biocon Bristol-Myers Squibb Research and Development Center, Biocon Park, Jigani Link Road, Bommasandra IV, Bangalore 560099, India

2. Chemical and Synthetic Development, Bristol-Myers Squibb Global Product Development and Supply, One Squibb Drive, P.O. Box 191, New Brunswick, New Jersey 08903-0191, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Reference31 articles.

1. Delmonte, A. J.; Cohen, B. M.; Fraunhoffer, K. J.; Kolotuchin, S.; Gonzalez-Bobes, F.; Beutner, G. L.; Freitag, A. J.; Bultman, M. S.; Fan, Y.; Maity, P.; Young, I. S.; Beck, H. P.; Ospov, M.; Powers, J. P.; Reilly, M. K.; Shunatona, H. P.; Walker, J. R.; Zibinsky, M. Substituted quinolinylcyclohexylpropanamide compounds and improved methods for their preparation. PCT Int. Appl. WO 2019006292 A1, 2019.

2. Direct Lewis Acid Catalyzed Conversion of Enantioenriched N-Acyloxazolidinones to Chiral Esters, Amides, and Acids

3. Rapid Development of a Commercial Process for Linrodostat, an Indoleamine 2,3-Dioxygenase (IDO) Inhibitor

4. Revisiting the Cleavage of Evans Oxazolidinones with LiOH/H2O2

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