Development, Optimization, and Scope of the Radiosynthesis of 3/5-[18F]Fluoropyridines from Readily Prepared Aryl(pyridinyl) Iodonium Salts: The Importance of TEMPO and K2CO3-Reference-Cited by-同舟云学术

Development, Optimization, and Scope of the Radiosynthesis of 3/5-[18F]Fluoropyridines from Readily Prepared Aryl(pyridinyl) Iodonium Salts: The Importance of TEMPO and K2CO3

Published:2019-04-11 Issue:5 Volume:23 Page:900-911
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Pauton Mathilde¹²,Aubert Catherine²,Bluet Guillaume²,Gruss-Leleu Florence²,Roy Sébastien²,Perrio Cécile¹^ORCID

Affiliation:

1. Normandie Univ, UNICAEN, CEA, CNRS, ISTCT UMR 6030, LDM-TEP, Cyceron, Boulevard Henri Becquerel, 14000 Caen, France

2. Sanofi R&D, 13 Quai Jules Guesde, 94403 Vitry sur Seine Cedex, France

Funder

Agence Nationale de la Recherche

Sanofi

Association Nationale de la Recherche et de la Technologie

Centre National de la Recherche Scientifique

Commissariat ? l'?nergie Atomique et aux ?nergies Alternatives

R?gion Normandie

Institut Normand de Chimie Mol?culaire, M?dicinale et Macromol?culaire

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.9b00021

Reference57 articles.

1. Pyridines and Imidazopyridines with Medicinal Significance

2. Roles of Pyridine and Pyrimidine Derivatives as Privileged Scaffolds in Anticancer Agents

3. Recent trends in the Chemistry of fluorinated five and six-membered heterocycles

4. Modern Fluoroorganic Chemistry

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Synthesis of K⁺channel radioligand [¹⁸F]5-methyl-3-fluoro-4-aminopyridine and PET imaging in mice;2024-07-19

2. Mutated Isocitrate Dehydrogenase (mIDH) as Target for PET Imaging in Gliomas;Molecules;2023-03-23

3. Nucleophilic Aromatic Substitution;Organic Reaction Mechanisms Series;2023-01-20

4. Oxidation-Cyclisation of Biphenyl Thioethers to Dibenzothiophenium Salts for Ultrarapid 18F-Labelling of PET Tracers;International Journal of Molecular Sciences;2022-12-07

5. Novel synthesis of an [18F]aryl boronic acid ester as a reagent for 18F-labeling via Suzuki coupling;Tetrahedron Letters;2022-08