The First GMP Synthesis of MK-2118, a Small Molecule Agonist for Stimulator of Interferon Genes-Reference-Cited by-同舟云学术

The First GMP Synthesis of MK-2118, a Small Molecule Agonist for Stimulator of Interferon Genes

Published:2024-05-30 Issue:6 Volume:28 Page:2309-2316
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Lyons Thomas. W.¹^ORCID,Thaisrivongs David A.²^ORCID,Kuhl Nadine²^ORCID,Chung Cheol K.²^ORCID,Angeles Angie²,Steinhuebel Dietrich²,Guetschow Erik³,Brunskill Andrew P. J.²,Henderson Timothy J.⁴,Cash Brandon D.⁴,Haidle Andrew⁴

Affiliation:

1. Department of Process Research and Development, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States

2. Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States

3. Department of Analytical Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States

4. Department of Discovery Chemistry, Merck & Co., Inc., Boston, Massachusetts 02115, United States

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.4c00102

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5. STING Agonists as Cancer Therapeutics

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