A Scalable Synthesis of Roxadustat (FG-4592)
Author:
Affiliation:
1. Zentiva k.s., U kabelovny 130, 102 00 Prague, Czech Republic
Funder
Zentiva k.s.
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.1c00281
Reference53 articles.
1. Hypoxia-Inducible Factor-Proline Hydroxylase Inhibitor in the Treatment of Renal Anemia
2. A New Approach to the Management of Anemia in CKD Patients: A Review on Roxadustat
3. Erythropoietin stimulating agents in the management of anemia of chronic kidney disease
4. Whether Prolyl Hydroxylase Blocker—Roxadustat—In the Treatment of Anemia in Patients with Chronic Kidney Disease Is the Future?
5. The efficacy and safety of roxadustat treatment for anemia in patients with kidney disease: a meta-analysis and systematic review
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1. Investigation on photo-isomeric impurity of Roxadustat: Structure conformation, physicochemical characterization, interconversion feasibility and in vitro toxicological evaluation;Journal of Molecular Structure;2024-02
2. In-Silico Aided Screening and Characterization Results in Stability Enhanced Novel Roxadustat Co-Crystal;Journal of Pharmaceutical Sciences;2023-10
3. Rh(III)-Catalyzed Reaction of 4-Diazoisochroman-3-imines with (2-Formylaryl)boronic Acids To Access a Straightforward Construction of 5H-Isochromeno[3,4-c]isoquinolines;The Journal of Organic Chemistry;2023-09-12
4. Structural characterization and in silico toxicity prediction of degradation impurities of roxadustat;Journal of Pharmaceutical and Biomedical Analysis;2023-09
5. A critical review of Roxadustat formulations, solid state studies, and analytical methodology;Heliyon;2023-06
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