Novel Strategy for Three-Dimensional Fragment-Based Lead Discovery
Author:
Affiliation:
1. Laboratory of Molecular Design and Drug Discovery, School of Basic Science, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, China.
Publisher
American Chemical Society (ACS)
Subject
Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ci200003c
Reference59 articles.
1. Fragment-based lead discovery
2. Making drugs on proteins: site-directed ligand discovery for fragment-based lead assembly
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4. Novel Inhibitors of DNA Gyrase: 3D Structure Based Biased Needle Screening, Hit Validation by Biophysical Methods, and 3D Guided Optimization. A Promising Alternative to Random Screening
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