A Novel Small-Molecule Inhibitor of the Avian Influenza H5N1 Virus Determined through Computational Screening against the Neuraminidase-Reference-Cited by-同舟云学术

A Novel Small-Molecule Inhibitor of the Avian Influenza H5N1 Virus Determined through Computational Screening against the Neuraminidase

Published:2009-04-15 Issue:9 Volume:52 Page:2667-2672
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

An Jianghong¹,Lee Davy C. W.¹,Law Anna H.Y.¹,Yang Cindy L.H.¹,Poon Leo L.M.¹,Lau Allan S.Y.¹,Jones Steven J.M.¹

Affiliation:

1. British Columbia Cancer Agency Genome Sciences Centre, 675 West 10th Avenue, Vancouver, British Columbia V5Z 4S6, Canada, Cytokine Biology Group, Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, China, and Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, China

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm800455g

Reference31 articles.

1. Avian Influenza Fact Sheet;World Health Organization:Geneva, 2006; http://www.who.int/mediacentre/factsheets/avian_influenza/en/index.html. Accessed 2006.

2. Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia

3. Evolution of H5N1 Avian Influenza Viruses in Asia

4. Influenza virus hemagglutinin concentrates in lipid raft microdomains for efficient viral fusion

Cited by 61 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Inhibitory Potentiality of Secondary Metabolites Extracted from Marine Fungus Target on Avian Influenza Virus-A Subtype H5N8 (Neuraminidase) and H5N1 (Nucleoprotein): A Rational Virtual Screening;VET ANIM SCI;2022

2. In quest of small-molecules as potent non-competitive inhibitors against influenza;Bioorganic Chemistry;2021-09

3. MXD1 regulates the H9N2 and H1N1 influenza A virus–induced chemokine expression and their replications in human macrophage;Journal of Leukocyte Biology;2020-08-13

4. Introducing Virtual Oligomerization Inhibition to Identify Potent Inhibitors of Aβ Oligomerization;Journal of Chemical Theory and Computation;2020-04-18

5. Mesoscale All-Atom Influenza Virus Simulations Suggest New Substrate Binding Mechanism;ACS Central Science;2020-02-19