Thiazolopyrimidinone Derivative H5–23 Enhances Daptomycin Activity against Linezolid-Resistant Enterococcus faecalis by Disrupting the Cell Membrane

Author:

Xiong Yanpeng12ORCID,Chen Zhong2ORCID,Bai Bing2,Peng Yalan1,Liu Shanghong2,Fang Di1,Wen Zewen2ORCID,Shang Yongpeng2,Lin Zhiwei23,Han Shiqing1,Yu Zhijian2

Affiliation:

1. College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, China

2. Department of Infectious Diseases and Shenzhen Key Laboratory for Endogenous Infections, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen Nanshan People’s Hospital and the Sixth Affiliated Hospital of Shenzhen University Medical School, Shenzhen 518052, China

3. Laboratory of Respiratory Disease, People’s Hospital of Yangjiang, Yangjiang 529500, China

Funder

Basic and Applied Basic Research Foundation of Guangdong Province

Science, Technology and Innovation Commission of Shenzhen Municipality

National Natural Science Foundation of China

Shenzhen Key Medical Discipline Construction Fund

Provincial medical funds of Guangdong

Shenzhen Nanshan District Scientific Research Program of the People?s Republic of China

Jiangsu Synergetic Innovation Center for Advanced Bio- Manufacture

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

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