Development of Amphiphilic Coumarin Derivatives as Membrane-Active Antimicrobial Agents with Potent In Vivo Efficacy against Gram-Positive Pathogenic Bacteria
Author:
Affiliation:
1. Key Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences & the Sixth Affiliated Hospital, Guangzhou Medical University, Guangzhou 511436, P. R. China
Funder
National Natural Science Foundation of China
Talent Fund for High-Level University Construction of Guangzhou
Publisher
American Chemical Society (ACS)
Subject
Infectious Diseases
Link
https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.1c00246
Reference50 articles.
1. Predictive compound accumulation rules yield a broad-spectrum antibiotic
2. Understanding the mechanisms and drivers of antimicrobial resistance
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4. A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance
5. Clinical, economic and societal impact of antibiotic resistance
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