Structure-Guided Design, Synthesis, and Evaluation of Guanine-Derived Inhibitors of the eIF4E mRNA

Structure-Guided Design, Synthesis, and Evaluation of Guanine-Derived Inhibitors of the eIF4E mRNA–Cap Interaction

Published:2012-04-18 Issue:8 Volume:55 Page:3837-3851
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chen Xiaoqi¹,Kopecky David J.¹,Mihalic Jeff¹,Jeffries Shawn¹,Min Xiaoshan¹,Heath Julie¹,Deignan Jeff¹,Lai SuJen¹,Fu Zice¹,Guimaraes Cristiano¹,Shen Shanling¹,Li Shyun¹,Johnstone Sheree¹,Thibault Stephen¹,Xu Haoda¹,Cardozo Mario¹,Shen Wang¹,Walker Nigel¹,Kayser Frank¹,Wang Zhulun¹

Affiliation:

1. Department of Chemistry Research & Discovery, §Department of Molecular Structure, ∥Department of Oncology, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, California 94080, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm300037x

Reference42 articles.

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