Design, Synthesis, Structural Studies, Biological Evaluation, and Computational Simulations of Novel Potent AT1 Angiotensin II Receptor Antagonists Based on the 4-Phenylquinoline Structure

Author:

Cappelli Andrea1,Pericot Mohr Gal.la1,Gallelli Andrea1,Rizzo Milena1,Anzini Maurizio1,Vomero Salvatore1,Mennuni Laura1,Ferrari Flora1,Makovec Francesco1,Menziani M. Cristina1,De Benedetti Pier G.1,Giorgi Gianluca1

Affiliation:

1. Dipartimento Farmaco Chimico Tecnologico and European Research Centre for Drug Discovery and Development, Università di Siena, Via A. Moro, 53100 Siena, Italy, Dipartimento di Scienze Farmacobiologiche, Università “Magna Græcia” di Catanzaro, Complesso “Ninì Barbieri”, 88021 Roccelletta di Borgia, Catanzaro, Italy, Rotta Research Laboratorium S.p.A., Via Valosa di Sopra 7, 20052 Monza, Italy, Dipartimento di Chimica, Università degli Studi di Modena e Reggio Emilia, Via Campi 183, 41100 Modena, Italy,...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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