Highly Reproducible Quantitative Proteomics Analysis of Pancreatic Cancer Cells Reveals Proteome-Level Effects of a Novel Combination Drug Therapy That Induces Cancer Cell Death via Metabolic Remodeling and Activation of the Extrinsic Apoptosis Pathway-Reference-Cited by-同舟云学术

Highly Reproducible Quantitative Proteomics Analysis of Pancreatic Cancer Cells Reveals Proteome-Level Effects of a Novel Combination Drug Therapy That Induces Cancer Cell Death via Metabolic Remodeling and Activation of the Extrinsic Apoptosis Pathway

Published:2023-10-31 Issue:12 Volume:22 Page:3780-3792
ISSN:1535-3893
Container-title:Journal of Proteome Research
language:en
Short-container-title:J. Proteome Res.

Author:

Rasam Sailee¹²,Lin Qingxiang³⁴,Shen Shichen²,Straubinger Robert M.²³⁴,Qu Jun¹²³⁴^ORCID

Affiliation:

1. Department of Biochemistry, University at Buffalo, Buffalo, New York 14260, United States

2. New York State Center of Excellence in Bioinformatics and Life Sciences, 701 Ellicott Street, Buffalo, New York 14203, United States

3. Department of Pharmaceutical Sciences, University at Buffalo, Buffalo, New York 14260, United States

4. Department of Cell Stress Biology, Roswell Park Comprehensive Cancer Center, Elm and Carlton Streets, Buffalo, New York 14203, United States

Funder

U.S. Department of Health and Human Services

U.S. Department of Defense

State University of New York

Center for Protein Therapeutics consortium grant

Publisher

American Chemical Society (ACS)

Subject

General Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jproteome.3c00463

Reference60 articles.

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2. Cancer Statistics, 2021

3. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial.

4. Phase II study of gemcitabine in patients with advanced pancreatic cancer

5. FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer

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