Incomplete Systemic Recovery and Metabolic Phenoreversion in Post-Acute-Phase Nonhospitalized COVID-19 Patients: Implications for Assessment of Post-Acute COVID-19 Syndrome

Author:

Holmes Elaine123ORCID,Wist Julien124ORCID,Masuda Reika1,Lodge Samantha12ORCID,Nitschke Philipp1,Kimhofer Torben12ORCID,Loo Ruey Leng2ORCID,Begum Sofina3,Boughton Berin12ORCID,Yang Rongchang1,Morillon Aude-Claire1,Chin Sung-Tong1,Hall Drew1,Ryan Monique1,Bong Sze-How1ORCID,Gay Melvin5,Edgar Dale W.67,Lindon John C.8ORCID,Richards Toby9,Yeap Bu B.10,Pettersson Sven111213,Spraul Manfred14,Schaefer Hartmut14,Lawler Nathan G.12ORCID,Gray Nicola12ORCID,Whiley Luke115ORCID,Nicholson Jeremy K.1216ORCID

Affiliation:

1. Australian National Phenome Centre, Health Futures Institute, Murdoch University, Harry Perkins Building, 5 Robin Warren Drive, Perth, WA 6150, Australia

2. Center for Computational and Systems Medicine, Health Futures Institute, Murdoch University, 5 Robin Warren Drive, Perth, WA 6150, Australia

3. Department of Metabolism, Digestion, and Reproduction, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, South Kensington, London SW7 2AZ, U.K.

4. Chemistry Department, Universidad del Valle, 76001 Cali, Colombia

5. Bruker Pty. Ltd., Preston, VIC 3072, Australia

6. State Adult Burn Unit, Fiona Stanley Hospital, Murdoch, WA 6150, Australia

7. Burn Injury Research Node, The University of Notre Dame, Fremantle, WA 6160, Australia

8. Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, London SW7 2AZ, U.K.

9. Department of Surgery, Fiona Stanley Hospital, Medical School, University of Western Australia,Harry Perkins Building, Murdoch, Perth, WA 6150, Australia

10. Department of Endocrinology and Diabetes, Fiona Stanley Hospital, Medical School, University of Western Australia, Harry Perkins Building, Murdoch, Perth, WA 6150, Australia

11. Singapore National NeuroScience Centre, Mandalay Road, Singapore 308232, Singapore

12. Lee Kong Chian School of Medicine. Nanyang Technological University, Mandalay Road, Singapore 308232, Singapore

13. Department of Life Science Centre, Sunway University, Kuala Lumpur 47500, Malaysia

14. Bruker Biospin GmbH, Ettlingen 76275, Germany

15. Perron Institute for Neurological and Translational Science, Nedlands, WA 6009, Australia

16. Institute of Global Health Innovation, Imperial College London, Level 1, Faculty Building, South Kensington Campus, London SW7 2AZ, U.K.

Funder

Medical Research Council

Australian Research Council

Government of Western Australia

Spinnaker Health Research Foundation

McCusker Foundation

Western Australia State Government

Medical Research Future Fund

Department of Jobs, Tourism, Science and Innovation, Government of Western Australia

Publisher

American Chemical Society (ACS)

Subject

General Chemistry,Biochemistry

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