Predicting Intrinsic Clearance for Drugs and Drug Candidates Metabolized by Aldehyde Oxidase
Author:
Affiliation:
1. Department of Chemistry, Washington State University, Pullman, Washington 99163, United States
2. Department of Pharmaceutical Sciences, Temple University School of Pharmacy, Philadelphia, Pennsylvania 19140, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Pharmaceutical Science,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/mp300568r
Reference28 articles.
1. Site Directed Mutagenesis of Amino Acid Residues at the Active Site of Mouse Aldehyde Oxidase AOX1
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4. Aldehyde Oxidase: An Enzyme of Emerging Importance in Drug Discovery
5. Increasing recognition of the importance of aldehyde oxidase in drug development and discovery
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